Reversal of impaired GIP and insulin secretion in patients with pancreatogenic steatorrhea following enzyme substitution

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Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.

We aimed to investigate how assimilation of nutrients affects the postprandial responses of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) and to evaluate the effect of pancreatic enzyme substitution (PES) on insulin secretion in patients with chronic pancreatitis (CP) and pancreatic exocrine insufficiency (PEI). Eight male patients with CP and PEI were s...

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ژورنال

عنوان ژورنال: Diabetologia

سال: 1980

ISSN: 0012-186X,1432-0428

DOI: 10.1007/bf00275269